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Reading the histone code
Shi Laboratory
The Shi Laboratory investigates the dynamic epigenetic mechanisms that regulate chromatin and transcription in an effort to better understand how they impact cancer development.
VAI News
FEATURED PUBLICATIONS
Wan L et al. ENL links histone acetylation to oncogenic gene expression in AML. Nature
Wen H et al. ZMYND11 links histone H3.3 K36 trimethylation to transcription elongation and tumor suppression. Nature
Li Y et al. AF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylation. Cell